True cost of sickle cell disease: $1.5 billion in lost productivity per year Sickle cell disease causes $1.5 billion in lost wages and productivity each year in the U.S. alone, according to the recent peer-reviewed study, titled “Indirect Economic Burden of Sickle Cell Disease” and published in the journal Value…..
A 100% French nasal vaccine against COVID-19 yields positive pre-clinical results In contrast to intramuscular vaccines, only nasal vaccines are able to block the virus in the nose by inducing local immunity in the nasal mucosa, i.e. the portal of entry and multiplication of the virus. The vaccine candidate, developed…..
Endeavor BioMedicines gains rights to lead ULK1/2 inhibitor molecule Endeavor BioMedicines, a clinical-stage precision medicine company targeting the core drivers of multiple terminal diseases, including oncology and fibrosis, has concluded an exclusive licensing agreement with the Salk Institute, along with Sanford Burnham Prebys. Under the license agreement, the California-based company…..
TreeFrog Therapeutics secures $75M in Series B financing to advance a pipeline of stem cell-derived cell therapies TreeFrog Therapeutics, a privately held French-based biotech startup focused on developing safe and affordable stem cell-derived cell therapies for millions of patients, today announced the successful closing of a $75 million (€64M) Series…..
Les intégrateurs industriels, futurs piliers de la filière Bioproduction ? La France s’est fixée pour objectif de devenir le leader européen de la bioproduction d’ici 2030. Emmanuel Dequier, directeur du Grand Défi « Biomédicaments : améliorer les rendements et maîtriser les coûts de production » nous décline les grands axes des travaux engagés par…..
Clean Biologics is acquiring Biodextris Clean Biologics, a French group providing services to the biopharmaceutical industry, is acquiring Biodextris, a Contract Development and Manufacturing Organization (CDMO) based in Laval (Montreal), Canada. Biodextris provides analytical and process development, early-phase clinical manufacturing and quality control testing services for clients in the vaccine…..
A Z-RNA nanoswitch encoded by "junk DNA" turns-off immune responses against self In a paper published in the May 13th, 2021 issue of PLOS Genetics, Dr. Alan Herbert of InsideOutBio, describes how nature uses a nano-scale Z-RNA switch to turn-off immune responses against self. This Z-RNA nanoswitch sequence, less than…..
Novel nanotech improves cystic fibrosis antibiotic by 100,000-fold Cystic fibrosis is causing severe impairments to a person's lungs, airways and digestive system, trapping bacteria and leading to recurrent infections. Lung failure is the major cause of death for people with this disease. World-first nanotechnology developed by the University of South…..
DNA Script Partners with Moderna to Develop On‐Demand Vaccines and Therapeutics for DARPA DNA Script, a disruptive DNA synthesis company engineering biology to accelerate breakthroughs in life science, is partnering with Moderna to develop a prototype for rapid mobile manufacturing of vaccines and therapeutics as part of the Defense Advanced…..
New research on why mutations in a gene leads to mitochondrial disease Image of mitochondria (yellow-green) around the cell nucleus (blue). ©Dr Matthew Eramo Mitochondrial diseases are inherited, chronic illnesses that can present at birth or develop later in life and occurs when mitochondria fail to produce enough energy for…..
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