3D cell and tissue cultures are an emerging field of biomedical research, enabling scientists to study the physiology of human organs and tissues in ways that have not been possible before. However, while these 3D cultures can be generated, technology that accurately assesses their functionality in real time has not…..
The genome editing system CRISPR has become a hugely important tool in medical research. The targeting system can travel to different points on the genome, guided by a short sequence of RNA, where the DNA-cutting enzyme Cas9 then makes the desired edits. However, CRISPR-Cas9 remains limited in the number of…..
The 2018 Nobel Prize in Physiology or Medicine has been jointly awarded to James P. Allison and Tasuku Honjo for their discovery of cancer therapy by inhibition of negative immune regulation. During the 1990s, in his laboratory at the University of California, Berkeley, James P. Allison studied the T-cell protein CTLA-4.…..