Why low DNA methylation at H3K27me3 sites for gene repression In our cells, genes associated with alternative cell fate have to be silenced. DNA methylation and H3K27me3 on the histone are two of the most prevalent chromatin modifications that control the epigenetic gene silencing. These two modifications are mutually exclusive…..
Demonstration of a potent, universal coronavirus monoclonal antibody therapy for all COVID-19 variant Researchers at University of Alabama at Birmingham (UAB), Texas Biomedical Research Institute and Aridis Pharmaceuticals discovered a neutralizing monoclonal antibody that potentially acts as a potent universal coronavirus therapy against SARS-CoV-2 and all its variants of concern,…..