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Agreements

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Date Company Compound Disease Type of agreement Therapeutic area Type of Information
2012-04-17 Labor L+S (Germany) Symbiosis, newly created unit of BioPharm (Germany) analytical services

collaboration

Collaboration agreement
2012-04-17 Angel Biotechnology (UK) TransGenRx (USA) recombinant interferon product

development

Development agreement
2012-04-17 GSK (UK) Five Prime Therapeutics (USA) refractory asthma
chronic obstructive pulmonary disease (COPD)

R&D

Respiratory diseases - Inflammatory diseases - Allergic diseases R&D agreement
2012-04-16 AstraZeneca (UK) Conformetrix (UK) Conformetrix’s proprietary NMR-based technology

R&D
services

R&D agreement
2012-04-16 Conformetrix (UK) AstraZeneca (UK) Conformetrix’s proprietary NMR-based technology R&D
collaboration
2012-04-12 Lonza (Switzerland) Agennix (Germany) talactoferrin non-small cell lung cancer

development
manufacturing
production

Cancer - Oncology Production agreement
2012-04-12 AstraZeneca (UK) Drugs for Neglected Diseases initiative (DNDi) novel drug candidates Chagas disease, leishmaniasis, sleeping sickness (human African trypanosomiasis)

R&D

Infectious diseases - Parasitic diseases R&D agreement
2012-04-12 Algeta (Norway) Bayer (Germany) Alpharadin® (radium-223 chloride)

promotion

Cancer Oncology Promotion agreement
2012-04-12 Seattle Genetics (USA - WA) Ventana Medical Systems (USA), a member of the Roche Group (Switzerland) molecular companion diagnostic test to evidentify patients who might respond to treatment with Adcetris® (brentuximab vedotin) based on CD30 expression levels in their tissue specimens CD30-positive cutaneous T-cell lymphoma (CTCL), CD30-positive mature T-cell lymphomas (MTCL)

collaboration
development
manufacturing
production
commercialisation

Cancer - Oncology Development agreement
2012-04-12 ImmunoGenes (Switzerland - Hungary) Amgen (USA) FcRn-overexpressing transgenic mice

R&D

R&D agreement
2012-04-12 Antitope (UK) Research Corporation Technologies (USA) toxic protein warhead for the next generation of antibody drug conjugates (ADCs) Cancer - Oncology R&D agreement
2012-04-11 Ipsen (France) Photocure (Norway) Hexvix® (hexaminolevulinate hydrochloride for intravesical solution) bladder cancer

licensing
commercialisation

Cancer - Oncology Milestone
2012-04-10 Immutep (France) Lonza (Switzerland) ImmuFact® IMP321  first line metastatic breast cancer

development

Cancer - Oncology Development agreement
2012-04-05 GSK (UK) Chiome Bioscience (Japan) monoclonal antibodies generated with Chiome’s proprietary ADLib® system cancer,autoimmune diseases

development

Autoimmune diseases - Cancer - Oncology Development agreement
2012-04-04 ImmunoGenes (Switzerland - Hungary) Amgen (USA) FcRn-overexpressing transgenic mice to generate antibodies against “difficult” antigen targets R&D agreement
2012-04-03 Roche (Switzerland) the French National Agency for Research on AIDS and Viral Hepatitis (ANRS - France) Baylor Research Institute (USA ) Inserm Transfert (France) therapeutic vaccines chronic infectious diseases

R&D
collaboration

Infectious diseases R&D agreement
2012-04-02 PolyTherics (UK) Spirogen (UK) antibody-drug conjugates (ADCs)

R&D

Cancer Oncology R&D agreement
2012-03-30 HTG Molecular Diagnostics (USA) Sanofi (France) biomarkers - molecular companion diagnostic test to help identify patients most likely to respond to a novel Sanofi investigational agent undisclosed

R&D

undisclosed R&D agreement
2012-03-29 Sanofi (France) Aviesan (France) Inserm Transfert (France) Institut Claudius Regaud (France) various undisclosed cancers

R&D

Cancer - Oncology R&D agreement
2012-03-28 Merck Serono (Germany) Bioseek (USA) use of BioMAP platform to evaluate Merck Serono small molecule compounds and proteins across multiple therapeutic areas in support of target differentiation, lead selection and optimization and nomination of candidates for preclinical development at Merck Serono

undisclosed

R&D

Multiple therapeutic areas R&D agreement