Date: 2012-07-24
Type of information: Grant
Company: Oxford Gene Technology (UK)
Investors:
Amount: €3 million
Funding type: grant
Planned used: EUCLIDS (EU Life-threatening Infectious Disease Study), is a 5-year, large-scale study to identify genomic variants that determine susceptibility to and severity of life-threatening bacterial infections in children, including meningococcal and pneumococcal cohorts. OGT has been awarded a grant of €1.1 million to perform high-throughput genomic analysis for the study, including whole exome sequencing, RNA sequencing, methylation analysis and microRNA analysis. OGT is part of an international consortium of 14 institutions in 6 countries, led by Professor Michael Levin at Imperial College, London. As leaders in targeted sequencing, OGT has also been awarded €1.9 million to design sequence enrichment methods and compare sequencing platforms for the PATHSEEK project. PATHSEEK is a 3-year study led by Professor Judy Breuer at University College London, which will demonstrate the potential of next generation sequencing technologies in clinical microbiology labs, to enable the detection of pathogens directly from clinical samples and the early detection of drug resistant mutations. The study will look at infections with clear unmet clinical need or which pose a global risk factor, including, HIV, mycobacterium tuberculosis, hepatitis B (HBV) and C (HCV) and influenza A.
Others: Oxford Gene Technology (OGT), provider of innovative clinical genetics and diagnostic solutions to advance molecular medicine, has announced that its next generation sequencing service team has been awarded two EU- funded clinical research grants worth €3 million. OGT will be providing genomic analysis and commercialisation services for two key international studies, EUCLIDS and PATHSEEK.
PATHSEEK will also investigate two host pharmacogenomics biomarkers which predict response to therapy for HCV and HIV. OGT have the rights to commercialise the final assay enrichment and sequencing panels for sale to clinical microbiology labs, strengthening its existing portfolio of clinical genomics products and services.
Therapeutic area: Infectious diseases
