Date: 2012-03-06
Type of information: Grant
Company: Telormedix (Switzerland)
Investors: CTI/KTI Programme (Switzerland)
Amount: CHF 1.37 Million
Funding type: grant
Planned used: The two-year research project is aimed at studying the molecular mode of action and interaction of Telormedix’s drug candidates with their specific Toll-like Receptor 7 (TLR7) target. The project will have a total budget of CHF 1.37 Million.
Others: Telormedix, a clinical stage biopharmaceutical company focused on TLR7 agonists in the treatment of cancer and inflammatory diseases, has received funding from the Swiss CTI/KTI Programme for collaboration with the University of Applied Sciences of Southern Switzerland (SUPSI). The two-year research project is aimed at studying the molecular mode of action and interaction of Telormedix’s drug candidates with their specific Toll-like Receptor 7 (TLR7) target. The project will have a total budget of CHF 1.37 Million.
The SUPSI team will be directed by Professor Andrea Danani, Head of Research at the Laboratory of Applied Mathematics and Physics in the Department of Innovative Technologies, whereas Telormedix’s contribution will be coordinated by Alcide Barberis, Head of Research and Collaborations. The project will focus on the characterization and optimization of target-specific interactions of TLR7 modulators and their mode of action in immune system cells. Computational modeling performed at SUPSI will provide theoretical information about the structure of the TLR7 receptor and domain-specific interactions with Telormedix’s compounds. Telormedix will then be able to accurately predict the biochemical and biological properties of select drug candidates, which will be further tested and verified in molecular and cellular studies.
Therapeutic area: Cancer - Oncology - Inflammatory diseases
