Clinical Trials

Date: 2017-12-14

Type of information: Initiation of the trial

phase:

Announcement: initiation of the trial

Company: Shire (UK - USA) Royal College of Surgeons Ireland (Ireland) Science Foundation Ireland (SFI) (Ireland) Irish Haemophilia Society (Ireland)

Product:

Action mechanism:

Disease: hemophilia

Therapeutic area: Rare diseases - Genetic diseases - Hematological diseases

Country: Ireland

Trial details:

Latest news:

• • On December 14, 2017, Shire, RCSI (Royal College of Surgeons Ireland), and Science Foundation Ireland (SFI), in collaboration with the Irish Haemophilia Society, jointly announced the initiation of a novel clinical study called “The Irish Personalised Approach to the Treatment of Haemophilia (iPATH).” Globally, approximately 187,000 people have been diagnosed with hemophilia, an inherited bleeding disorder.
• Instead of focusing on standardized treatments, the iPATH study seeks to take the next step in treatment and will investigate new personalized treatment approaches by tailoring care based on the needs of individual patients.
• Patients in Ireland with hemophilia are registered at a single National Coagulation Centre where data on the use of factor concentrates and bleeding rates have already been collected. This provides a unique opportunity to conduct a hemophilia study aimed at better understanding the underlying biology of hemophilia with the goal of developing a personalized approach to hemophilia care that can then potentially be extended to the global hemophilia community. This clinical study approach also has the potential to be adapted for other diseases.
• The iPATH study will take place over a four-year period. The study is supported by an SFI Strategic Partnership initiative and involves scientific researchers in RCSI, Trinity College Dublin (TCD) and Shire, based on its strong and established presence in Ireland. The iPATH partnership also includes clinical researchers based in St James’s Hospital Dublin, Our Lady’s Children’s Hospital Crumlin, Cork University Hospital and University Hospital Galway.

Is general: Yes