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Clinical Trials

Date: 2014-11-25

Type of information: Publication of results in a medical journal

phase: preclinical

Announcement: publication of results in PLOS ONE

Company: Valneva (France)

Product: VLA15 - Lyme borreliosis vaccine

Action mechanism:  vaccine. Valneva’s vaccine candidate is a multivalent OspA based vaccine.

Disease: Lyme borreliosis

Therapeutic area: Infectious diseases

Country:

Trial details:

Latest news:

  • • On November 25, 2014, Valneva announced that an article, presenting for the first time the preclinical data of its novel vaccine candidate for prevention of Lyme borreliosis, was published in PLOS ONE. The article entitled: “Design and development of a novel vaccine for protection against Lyme borreliosis” details for the first time Valneva´s Borrelia/Lyme borreliosis vaccine approach, with design, proof-of-concept studies and preclinical data on protection. The publication reveals that Valneva’s vaccine candidate, a multivalent, protein subunit based vaccine, has the potential to provide protection against the majority of Borrelia species pathogenic for humans. The Borrelia program is part of the strategic alliance agreement signed in 2007 with Novartis. Under this agreement, Novartis gets opt-in rights for the development, manufacturing and commercialization of Valneva Austria GmbH’s non-partnered novel vaccine candidates after the completion of Phase II clinical trials (or earlier at Novartis’s discretion).

Is general: Yes