Date: 2017-12-18
Type of information: Development agreement
Compound: novel adeno-associated virus (AAV) vectors, packaging and producer cell lines
Company: Oxford Genetics (UK) MeiraGTx (USA - NY)
Therapeutic area: Rare diseases - Genetic diseases - Technology - Services
Type agreement: development - manufacturing - production
Action mechanism: gene therapy
Disease:
Details:
- • On December 18, 2017, MeiraGTx, a London and New York-based gene therapy company, has established a new collaboration with Oxford Genetics, a leader in innovative synthetic biology-based technologies for biologics discovery, development and delivery. The collaboration will enable MeiraGTx and Oxford Genetics to develop novel adeno-associated virus (AAV) vectors, as well as packaging and producer cell lines to support the manufacturing needs of MeiraGTx’s pipeline of gene therapy product candidates. The companies aim to create a fully scalable AAV production system that can satisfy the requirements for increased viral vector yields, process robustness and product efficacy. As part of the agreement, MeiraGTx gains exclusive, worldwide research and manufacturing rights to novel serotype specific AAV vectors, along with associated packaging and producer cell lines.
- Located in central London, and under the direction of industry experts James Christie and Ian Delmage, MeiraGTx’s state-of-the-art manufacturing facility is designed for parallel manufacture of multiple products through the establishment of multiple production trains. MeiraGTx’s manufacturing hub also incorporates Process Development suites and Fill and Finish capability. This 29,000 sq ft facility is designed to meet MHRA, EMA and FDA regulatory standards, supporting MeiraGTx’s global view toward clinical development and market supply. This unique facility will provide a nucleus for the development of novel processes and analytics as well as a center for collaboration with technology experts in Gene Therapy and Bioprocessing.
Financial terms:
Latest news:
Is general: Yes
