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Date Company Compound Disease Type of agreement Therapeutic area Type of Information
2014-01-19 uniQure (The Netherlands) 4D Molecular Therapeutics (USA - CA) adeno-associated viral (AAV) vector discovery and optimization technology for gene delivery to the central nervous system and liver.

licensing

collaboration

CNS diseases - Liver diseases - Hepatic diseases Licensing agreement
2014-01-17 Axxam (Italy) Cellectis bioresearch (France)

collaboration

Technology - Services Collaboration agreement
2014-01-17 Shire (UK-USA) Organogenesis (USA) Dermagraft® assets diabetic foot ulcers

product acquisition

Metabolic diseases Product acquisition
2014-01-16 Horizon Discovery (UK) Transgenomic (USA) improved genetic diagnostic tests

collaboration

Diagnostic Collaboration agreement
2014-01-15 Sanofi (France) Fraunhofer-Gesellschaft (Germany) natural product center of excellence infectious diseases

R&D

Infectious diseases R&D agreement
2014-01-15 Helsinn (Switzerland) Angelini (Italy) anamorelin anorexia-cachexia in non small lung cell cancer (NSLC)

commercialisation

Cancer - Oncology Commercialisation agreement
2014-01-14 Genmab (Denmark) Lilly (USA - IN) DuoBody™ technology platform for the creation of bispecific antibodies

R&D

Technology - Services R&D agreement
2014-01-14 Ipsen (France) GW Pharmaceutical (UK) Sativex® (Delta-9-Tetrahydro-cannabinol (THC) and Cannabidiol (CBD) spasticity due to multiple sclerosis

promotion
distribution

Neurodegenerative diseases Distribution agreement
2014-01-14 Onkaido Therapeutics, Moderna Therapeutics' company (USA - MA) vice president nomination Cancer - Oncology Nomination
2014-01-13 AstraZeneca (UK) Ardelyx (USA) NHE3 inhibitor programme including tenapanor, RDX5791 complications of renal disease, including diabetes-induced renal disease, chronic kidney disease

licensing

Kidney diseases - Renal diseases - Metabolic diseases Milestone
2014-01-13 Cell Therapeutics (USA) Novartis (Switzerland) Opaxio™ (paclitaxel poliglumex), Pixuvri® (pixantrone) multiply relapsed or refractory aggressive B-cell non-Hodgkin lymphoma

licensing
sale

Cancer - Oncology Licensing agreement
2014-01-13 Bayer (Germany) Regeneron Pharmaceuticals (USA - NY) Platelet Derived Growth Factor Receptor Beta (PDGFR-Beta) antibody potential combination therapy with Eylea® (aflibercept) wet age-related macular degeneration (wet AMD)

development

Ophtalmological diseases Development agreement
2014-01-13 Diaxonhit (France) Samsung (South Korea) point of care diagnostic tests (IB10, PT10 and HC10 equipment together with associated reagents)

distribution

Distribution agreement
2014-01-13 Jazz Pharmaceuticals (Ireland) Aerial Biopharma (USA) ADX-N05 excessive daytime sleepiness in patients with narcolepsy

licensing
sale

Rare diseases Licensing agreement
2014-01-13 Prosensa (The Netherlands) GSK (UK) drisapersen (previously GSK2402968/PRO051) and other DMD programmes Duchenne muscular dystrophy

licensing
rights

Genetic diseases - Neuromuscular diseases - Rare diseases Termination of an agreement
2014-01-13 Argen-X (The Netherlands-Belgium) Boehringer Ingelheim (Germany)

R&D

undisclosed R&D agreement
2014-01-13 Galapagos (Belgium) Mimetas (The Netherlands) organ-on-a-chip-based human disease models

R&D

Technology - Services R&D agreement
2014-01-13 Lonza (Switzerland) Pharmacyclics (USA) Imbruvica™ (ibrutinib)

manufacturing
production

Cancer - Oncology Production agreement
2014-01-13 Trianta Immunotherapies (Germany) Ascenion (Germany) personalized dendritic cell vaccines and adoptive T-cell therapies

licensing

Cancer - Oncology Licensing agreement
2014-01-13 UCB (Belgium) MRC Technology (UK) fibrosis therapy program fibrosis

development
licensing

Development agreement