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Fragile X syndrome begins developing even before birth

Fragile X syndrome begins developing even before birth Fragile X syndrome (FXS), the most common form of inherited intellectual disability, may be unfolding in brain cells even before birth, despite typically going undiagnosed until age 3 or later. These results could fundamentally change how scientists understand the developmental origins of…..

Drug discovery on an unprecedented scale

Drug discovery on an unprecedented scale [caption id="" align="aligncenter" width="700"] Artistic impression of artificial intelligence in drug design - ©Ina Pöhner[/caption] Boosting virtual screening with machine learning allowed for a 10-fold time reduction in the processing of 1.56 billion drug-like molecules. Researchers from the University of Eastern Finland teamed up with industry…..

Good news for quality control of mRNA medications

Good news for quality control of mRNA medications A mRNA molecule (p-RNA) is mixed with a standard (s-RNA) labelled with stable isotopes (SI) before being digested then characterized using a combination of liquid chromatography and mass spectrometry (LC-MS). The output is analyzed using Ariadne software to yield information on the…..