Date | Compound | Laboratory | Indication | Type of Information |
---|---|---|---|---|
2017-06-07 | Iodine (131I) murine IgG1 monoclonal antibody against CD276 | Memorial Sloan Kettering Cancer Center (USA - NY) Y-mAbs Therapeutics (USA - NY) | neuroblastoma | Granting of the Breakthrough Therapy status |
2016-08-22 | stabilized sulforaphane | Evgen Pharma (UK) | subarachnoid hemorrhage |
Granting of the orphan status in the US |
2016-06-01 | aducanumab | Biogen (USA - MA) | Alzheimer’s disease | Granting of a Fast Track status |
2016-06-01 | gallium [Ga-68]-N-[(4,7,10-tricarboxymethyl-1,4,7,10-tetraazacyclododec-1-yl)acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophanyl-L-lysyl-L-threoninyl-Lcysteinyl-L-threonine-cyclic(2-7)disulfide | Advanced Accelerator Applications SA (France) | diagnosis of gastro-entero-pancreatic neuroendocrine tumours |
Granting of a Market Authorisation in the US |
2017-05-09 | (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate | Loxo Oncology (USA - CT) | unresectable or metastatic solid tumors with NTRK-fusion proteins in adult and pediatric patients who require systemic therapy and who have either progressed following prior treatment or who have no acceptable alternative treatments | Granting of the orphan status in the US |
2016-11-03 | H-(4-amino-3-iodo)-D-Phe-c[Cys-(3-iodo)-Tyr-D-Trp-Lys-Val-Cys]-Thr-NH2 | Amryt Research (Ireland) | acromegaly |
Granting of the orphan status in the US |
2016-10-04 | posaconazole | Merck&Co (USA - NJ) | invasive aspergillosis |
Granting of a patent |
2016-11-02 | 2-amino-3-[3-[[4-(2-pyridyloxymethyl)phenyl]methyl]isoxazol-5-yl]pyridin-1-ium-1-yl]methyl hydrogen phosphate | Amplyx Pharmaceuticals (USA - CA) | invasive rare mold infections caused by scedosporium spp., fusarium spp., and mucorales fungi (including mucor spp., and rhizopus spp.)
|
Granting of the orphan status in the US |
2016-10-19 | 2-amino-3-[3-[[4-(2-pyridyloxymethyl)phenyl]methyl]isoxazol-5-yl]pyridin-1-ium-1-yl]methyl hydrogen phosphate | Amplyx Pharmaceuticals (USA - CA) | invasive candidiasis |
Granting of the orphan status in the US |
2016-11-03 | 2-amino-3-[3-[[4-(2-pyridyloxymethyl)phenyl]methyl]isoxazol-5-yl]pyridin-1-ium-1-yl]methyl hydrogen phosphate | Amplyx Pharmaceuticals (USA - CA) | coccidioidomycosis |
Granting of the orphan status in the US |
2016-10-26 | 2-amino-3-[3-[[4-(2-pyridyloxymethyl)phenyl]methyl]isoxazol-5-yl]pyridin-1-ium-1-yl]methyl hydrogen phosphate | Amplyx Pharmaceuticals (USA - CA) | invasive aspergillosis |
Granting of the orphan status in the US |
2016-05-18 | 2-amino-N-({methyl-[(6-trifluoromethoxy-benzothiazol-2-ylcarbamoyl)-methyl]-carbamoyl}-methyl)-acetamide monohydrochloride | Biohaven Pharmaceuticals (USA - CT) | spinocerebellar ataxia |
Granting of the orphan status in the US |
2016-10-11 | 2-[4-[[(2R)-2-ethoxy-3-[4-(trifluoromethyl)phenoxy]propyl]thio]-2-methylphenoxy]acetic acid (1:1) lysine dihydrate | Cymabay Therapeutics (USA - CA) |
|
Granting of a patent |
2016-11-09 | 2-[4-[[(2R)-2-ethoxy-3-[4-(trifluoromethyl)phenoxy]propyl]thio]-2-methylphenoxy]acetic acid (1:1) lysine dihydrate | Cymabay Therapeutics (USA - CA) | primary biliary cholangitis | Granting of a patent |
2016-12-13 | 3-aminopropyl-butyl phosphinic acid | Speragen (USA - TX) | succinic semialdehyde dehydrogenase deficiency |
Granting of the orphan status in the US |
2016-09-06 | 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol | Ovid Therapeutics (USA - NY) | Angelman syndrome |
Granting of the orphan status in the US |
2018-04-23 | adenovirus associated viral vector serotype 5 containing the RPGR gene | MeiraGTx (USA - NY) | retinitis pigmentosa | Granting of a Fast Track status |
2016-07-05 | adenovirus-associated viral vector serotype 5 containing the human pde6B gene | Horama (France) | retinitis pigmentosa due to pde6B gene mutations |
Granting of the orphan status in the US |
2016-12-05 | 5-{[(3R,4R)-1-(4-chloro-2,6-difluorophenyl)-3,4-dihydroxypiperidin-4-yl]methoxy}-8-fluoro-3,4-dihydroquinolin-2(1H)-one | Otsuka Pharmaceutical (Japan) | active tuberculosis |
Granting of the orphan status in the US |
2016-11-03 | 6'-(R)-Methyl-5-O-(5-amino-5,6-dideoxy-a-L-talofuranosyl)- paromamine sulfate | Eloxx Pharmaceuticals (Israel) | Rett syndrome |
Granting of the orphan status in the US |
© 2024 Biopharmanalyses - Powered by Samacom+