Date: 2017-03-09
Type of information: Nomination
Compound: chief executive officer, chief operating officer, chief development officer, members of the board of directors
Company: Dynacure (France)
Therapeutic area: Rare diseases - Genetic diseases
Type agreement: nomination
Action mechanism:
Disease:
Details:
- • On March 9, 2017, Dynacure announced the appointment of its new management team and members of the board of directors. The leadership team includes Stephane van Rooijen (CEO), Frédéric Legros (COO) and Leen Thielemans (Head of Development). The team will focus on the company’s preclinical and clinical development programs in Centronuclear Myopathies (CNM) and the expansion of its pipeline in rare disease treatments.
- Stephane van Rooijen has an extensive experience in the life sciences orphan biotech industry, previously working at Genzyme, Viropharma-Shire and Confo Therapeutics. He has a medical degree from the University of Leuven in Belgium and obtained an MBA at the Erasmus University Rotterdam and Georgetown University of Washington DC.
- Frédéric Legros has over a decade of experience in business development and strategic management. Before joining Dynacure, Frédéric was Vice President and Corporate Head of Business Development at Valneva. Frédéric obtained his PhD in molecular biology in 2002 at the Institute of Myology in Paris. He also holds a business degree from NEOMA business school, France.
- Leen Thielemans, Head of Development, brings with her over fifteen years of experience in pharmaceutical R&D, from drug discovery to early clinical development. Leen previously worked at Johnson & Johnson, 4AZAElbion, Movetis, and Shire. Leen Thielemans is a bio-engineer from the University of Leuven and an epidemiologist with a PhD in medical sciences.
- Dynacure’s Board of Directors has six members: Frederic Chereau, Chris Mirabelli and Brett Monia, who have been appointed as independent directors, Rémi Droller and Vanessa Malier, who represent Kurma Partners, and Stephane van Rooijen (CEO).
- Frederic Chereau is President and CEO of LogicBio. He has over 25 years of experience and acknowledged leadership in the orphan life sciences industry and previously worked at aTyr, Shire, Pervasis and Genzyme. He holds a B.S. in Physics from Paris University and obtained a Master’s degree in Management from La Rochelle Business School in France and an M.B.A. from INSEAD, Fontainebleau, France.
- Chris Mirabelli , CEO and Chairman of the Board of Directors of Leap Therapeutics, is an internationally-recognized biotech entrepreneur. He was a co-founder of Ionis Pharmaceuticals and currently holds board positions in a number of US biotechnology companies. He received his PhD in Molecular Pharmacology from the Baylor College of Medicine and obtained a B.S. degree in Biology from the State University of New York at Fredonia.
- Brett Monia (PhD), Senior Vice President of Antisense Drugs Discovery at Ionis Pharmaceuticals, is a founding member of Ionis. He is the Franchise Leader for programs in Oncology and Rare Genetic Diseases, and head of Drug Discovery at Ionis Pharmaceuticals. Dr. Monia received his PhD in Pharmacology at the University of Pennsylvania and holds B.S. degrees in Molecular Biology and Analytical Chemistry
- Dynacure is a biotechnology company developing new treatments for patients affected by serious orphan disorders. In its first drug discovery program, Dynacure is focusing on Centronuclear Myopathies (CNM), a rare, debilitating disease affecting children and young adults. Dynacure’s Dyn101 development program is based on the modulation of the expression of the Dynamin 2 protein through the use of an antisense oligonucleotide developed in collaboration with Ionis Pharmaceuticals, the leading biopharmaceutical company in RNA-targeted drug discovery. Dynacure was founded in 2016 as a spin-off from the IGBMC (Institute of Genetic and Molecular and Cellular Biology – Unistra/INSERM/CNRS) of Strasbourg.
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