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Agreements

Date: 2016-11-02

Type of information: Development agreement

Compound: monoclonal antibodies

Company: Leo Pharma (Denmark) Morphosys (Germany)

Therapeutic area: Cancer - Oncology - Dermatological diseases

Type agreement:

development

Action mechanism:

monoclonal antibody

Disease:

Details:

* On November 2, 2016, MorphoSys  and LEO Pharma today announced that they have entered into a strategic alliance for the discovery and development of therapeutic antibodies for the treatment of skin diseases. The objective of the alliance is to identify novel, antibody-based therapeutics for unmet medical needs that will be valuable additions to both companies' pipelines.
Collaborating on multiple targets selected by LEO Pharma, the two companies will work together to identify, validate and develop novel therapeutic antibodies. MorphoSys will apply its proprietary Ylanthia technology to generate fully human antibody candidates against the selected targets and will conduct all development activities up to the start of clinical testing. LEO Pharma will be responsible for clinical development and commercialization of resulting drugs in all indications outside of cancer. In skin cancer indications, MorphoSys will have options to co-develop and, in Europe, co-promote the respective antibody drugs. In addition, MorphoSys will have certain options to develop and commercialize programs arising from the collaboration in other cancer indications.

Financial terms:

MorphoSys will receive R&D funding as well as success-based development, regulatory and commercial milestone payments, plus royalties on net sales of drugs commercialized by LEO Pharma. Assuming all development, regulatory and sales objectives are reached, milestone payments would sum up to € 111.5 million per antibody program.

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