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Date: 2014-11-18

Type of information: Development agreement

Compound: next-generation sequencing (NGS) epidemiology solution for service labs

Company: Illumina (USA - CA) bioMérieux (France)

Therapeutic area: Technology - Services - Infectious diseases

Type agreement:

development

Action mechanism:

Disease:

Details:

* On November 18, 2014, bioMérieux, a world leader in the field of in vitro diagnostics, and Illumina, a world leader in genomics, announced they have signed an exclusive agreement to launch a next-generation sequencing (NGS) epidemiology solution for service labs. The two companies will jointly develop applications for microbiology sequencing technologies within a four-year renewable period.
The first application will be an NGS epidemiological solution offered by service labs for genotyping disease agents. The high resolution of NGS combined with bioMerieux’s industry-leading knowledge in microbiology will provide easily accessible and highly accurate information to communities and hospitals to track, prevent, contain and stop the spread of disease agents. The solution will combine Illumina’s MiSeq® sequencing system with a jointly developed pathogen genome database based on bioMérieux’s culture collection. This collection, which contains over 80,000 references, constitutes one of the largest libraries of bacterial strains in the world, and will contribute to creating a database with information about virulence and microbial resistance characteristics. The service will deliver a standardized report with a genomic profile of the infectious agents, with sequence-level accuracy and depth of information.

The ultimate goal of the Illumina-bioMérieux epidemiology solution will be to enable public health and hospital microbiology laboratories to contain an epidemic, avoid transmission of infectious agents, and improve hospital practices where needed. Those facing a suspected epidemic or health crisis will be able to send the relevant isolates to a designated laboratory equipped with an Illumina sequencing system. The genetic sequences will be sent via a secure cloud platform to be analyzed, using the database and software developed by bioMérieux, which will also generate a customized report for the customer. The precise results will be presented seamlessly, in an easily understandable graphical format identifying the infectious agent as well as the sequence-based genetic variations that would assist in understanding its transmission.

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