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Agreements

Date: 2014-10-16

Type of information: Collaboration agreement

Compound:

Company: AstraZeneca (UK) the University of Cambridge (UK)

Therapeutic area: Neurodegenerative diseases - Cancer - Oncology

Type agreement:

collaboration

Action mechanism:

Disease:

Details:

* On October 16, 2014, AstraZeneca, together with its global biologics research and development arm, MedImmune, announced that it has entered into four new collaborations with the University of Cambridge, building further on their existing partnership. The latest collaborations reinforce AstraZeneca’s commitment to creating a permeable research infrastructure in Cambridge following the company’s decision to locate one of its three global research and development centres and its global headquarters in the city that has been home to MedImmune’s biologics research laboratories for 25 years. The agreements build on the existing strategic partnership between AstraZeneca, MedImmune and the University of Cambridge, which includes a substantial oncology research programme and co-location of AstraZeneca scientists at the Cancer Research UK Cambridge Institute, the largest single facility conducting cancer research in the University of Cambridge. The four agreements involve:

Neuroscience research: A three-year collaboration between AstraZeneca, MedImmune and the University of Cambridge will focus on advancing research and development in neurodegenerative diseases. Scientists from all three parties will collectively address gaps in drug discovery, translational biomarkers and personalised healthcare approaches for diseases such as Alzheimer’s, Parkinson’s and multiple sclerosis. The University of Cambridge will contribute world-leading expertise in disease biology, experimental models and tissue samples, while AstraZeneca and MedImmune will provide access to molecular tools, screening capabilities and leading drug development expertise to enable novel target and biomarker discovery and validation. The research will be carried out at MedImmune and the University of Cambridge laboratories, with opportunities for investigators to work alongside each other and share knowledge.

Access to AstraZeneca pipeline compounds: A pivotal Material Transfer Agreement (MTA) will give researchers from the University of Cambridge access to key compounds from AstraZeneca’s pipeline for investigation, such as the EGFR inhibitor AZD9291 for non-small cell lung cancer, olaparib, a PARP inhibitor, AZD2014, an mTOR inhibitor and AZD5363, an AKT inhibitor.

PhD programme to support future leaders in science: The collaboration between MedImmune and the University of Cambridge includes a doctoral training programme whereby PhD candidates will spend significant time at the University of Cambridge and in MedImmune’s laboratories, jointly supervised by the organisations during their four-year studentship.

Entrepreneur-in-residence programme: This programme will offer guidance and mentorship to academic researchers at the University of Cambridge who are considering the broader application and commercial potential of their scientific programmes. MedImmune will provide support and advice on a range of key issues tailored to the individual academic’s needs such as drug and technology development, business planning, intellectual property, market opportunity, partnering approaches and securing investment.

 

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Is general: Yes