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Agreements

Date: 2014-01-03

Type of information: R&D agreement

Compound: cyclin-dependent kinase 9 (CDK9) inhibitor program

Company: Probiodrug (Germany) AstraZeneca (UK)

Therapeutic area: Cardiovascular diseases - Inflammatory diseases

Type agreement:

sale

Action mechanism:

Disease:

Details:

* On January 3, 2014, Probiodrug has announced the transfer of its experimental cyclin-dependent kinase 9 (CDK9) inhibitor program to AstraZeneca. The transaction includes the sale to AstraZeneca of a lead molecule and back-up compounds with the associated intellectual property. CDK9, which has been implicated in the transcriptional regulation of genes involved in proliferation and inflammation, is a promising target for the treatment of both cancer and inflammatory diseases.

Financial terms:

Financial terms of the asset purchase were not disclosed. Probiodrug was advised by UP Biotech Management AG in this transaction.

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Is general: Yes