Date: 2013-10-11
Type of information: Licensing agreement
Compound: antibody-drug conjugate (ADC) technology
Company: ImmunoGen (USA) Novartis (Switzerland)
Therapeutic area: Cancer - Oncology
Type agreement: licensing
Action mechanism: The Company’s ADC technology uses a tumor-targeting engineered antibody to deliver one of ImmunoGen\'s highly potent cancer-cell killing agents specifically to tumor cells.
Disease:
Details: * On October 11, 2013, ImmunoGen, a biotechnology company that develops novel anticancer therapeutics using its antibody-drug conjugate (ADC) technology, has announced that Novartis has licensed the exclusive right to use the Company\'s ADC technology to develop anticancer therapeutics to an undisclosed target.
The most advanced compound with ImmunoGen\'s ADC technology is Roche’s Kadcyla®, which is marketed in the US by Genentech and also gaining approvals internationally. ImmunoGen has four wholly owned clinical-stage product candidates, with additional compounds in the clinic through its partnerships with Amgen, Bayer HealthCare, Biotest and Sanofi (SAR3419).
Financial terms: This is the second license to be taken by Novartis under a 2010 agreement between the companies. For each license, ImmunoGen receives an upfront payment and is entitled to receive milestone payments potentially totaling approximately $200 million plus royalties on the sales of any resulting products. Novartis is responsible for the development, manufacturing and marketing of any products resulting from the license.
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