Date: 2013-06-10
Type of information: Licensing agreement
Compound: Drosophila Schneider-2 cell-based technology platform - ExpreS2 - for protein production
Company: ExpreS2ion Biotechnologies (Denmark) Cancer Research UK’s London Research Institute (UK)
Therapeutic area: Technology - Services
Type agreement: licensing
Action mechanism: ExpreS2ion Biotechnologies has developed a complete proprietary protein expression platform, ExpreS2, based on engineered Drosophila Schneider-2 (S2) cells to serve recombinant protein production needs in the biopharmaceutical industry as well as in academia. ExpreS2 allows quick access to proteins, excellent protein expression capability, scalability, applicability to high cell density production processes and regulatory friendliness. ExpreS2ion Biotechnologies is collaborating with teams developing manufacturing processes for malaria recombinant subunit vaccines. Expression of notoriously challenging malaria proteins in ExpreS2 platform has enabled progress in these projects that address a huge medical need. ExpreS2ion Biotechnologies offers technology platform licensing opportunities for use in R&D and commercial protein manufacturing.
Disease:
Details: ExpreS2ion Biotechnologies and the Protein Purification Facility at Cancer Research UK’s London Research Institute have signed a research license agreement to provide the Protein Purification Facility at Cancer Research UK’s London Research Institute with access to its Drosophila Schneider-2 cell-based technology platform - ExpreS2 - for protein production. The stable, non-lytic protein expression platform, which is fully cGMP compatible, will complement the existing capabilities in protein expression at the Protein Purification Facility. The platform will be used to address expression of complex and “challenging” proteins, including Fab fragments and other proteins. This license is a relevant addition to ExpreS2ion Biotechnologies’ vision of making its production platform available to academic centers of excellence globally, in complement to the Company’s strategy of making S2 one of the standard protein production platforms in the immunotherapy and therapeutic protein segments.
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