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Agreements

Date: 2013-05-14

Type of information: Development agreement

Compound: RYI-008

Company: CMC Biologics (Denmark) RuiYi (China)

Therapeutic area:

Type agreement:

development

Action mechanism:

RYI-008, formerly ARGX-109, is a novel, extremely potent monoclonal antibody that is highly selective to IL-6, a cytokine widely implicated in inflammation and cancer. The antibody was discovered by arGEN-X, Ghent Belgium, utilizing the arGEN-X SIMPLE AntibodyTM technology, and exclusively license to RuiYi to develop and commercialize globally.

Disease:

Details:

CMC Biologics has announced the execution of an agreement with RuiYi Inc. to develop a cell line for RYI-008, a novel anti-IL-6 monoclonal antibody. CMC Biologics’ proprietary CHEF1® high-productivity expression plasmid will be utilized for the cell line development to optimize cell growth, and consistent, high-level protein expression in a rapid time frame. Specific terms of the agreement were not disclosed.

Financial terms:

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Is general: Yes