Good news for quality control of mRNA medications A mRNA molecule (p-RNA) is mixed with a standard (s-RNA) labelled with stable isotopes (SI) before being digested then characterized using a combination of liquid chromatography and mass spectrometry (LC-MS). The output is analyzed using Ariadne software to yield information on the…..
Creation of the Institut Pasteur-UCSF QBI Center of Excellence in Emerging Infectious Diseases Two academic and scientific heavyweights, the Institut Pasteur and UC San Francisco Quantitative Biosciences Institute (UCSF QBI), agree to implement joint actions towards the creation of a center of excellence in emerging infectious diseases with planned operations/locations…..
Longer life due to faulty RNA processing [caption id="" align="aligncenter" width="700"] The roundworm Caenorhabditis elegans is an important model organism in ageing research. The worm in the image is labelled with GFP::RNP-6. Credit: Max Planck Institute for Biology of Ageing[/caption] RNA is an important transmitter of information in our cells…..
Pegcetacoplan treatment shows increased effects over time in geographic atrophy Pegcetacoplan, a targeted C3 therapy designed to regulate excessive activation os the complement cascade, is on track to become the first treatment for geographic atrophy (GA) with a PDFU date of Nov. 26 and EU MAA submission on track by…..
China'BGI Genomics exports its thalassemia detection kits in Azerbaijan Azerbaijan Thalassemia Center will be one of Chinese BGI's pioneer overseas thalassemia projects in a country with a high prevalence rate of this disease. On 6th September 2022, the Azerbaijan Thalassemia Center and BGI Genomics held a virtual signing ceremony to…..
Genomics study identifies unique set of proteins that restores hearing in zebrafish Study shows the role of transcription factors in facilitating cell regeneration. National Institutes of Health researchers have discovered a specific network of proteins that is necessary to restore hearing in zebrafish through cell regeneration. The study, led by…..
NIH researchers develop gene therapy for rare ciliopathy Researchers from the National Eye Institute (NEI), part of the National Institutes of Health (NIH), have developed a gene therapy that rescues cilia defects in retinal cells affected by a type of Leber congenital amaurosis (LCA), a disease that causes blindness…..
Carroucell has raised €1.5 million Carroucell, a French microcarrier supplier for cell culture in bioreactor, has raised a total of €1.5 million. The funding includes the closing of a Series A financing, led by the Novalis Biotech Acceleration fund and with participation of Crédit Agricole des Savoie (CADS), as well…..
KU Leuven spin-off AstriVax raises € 30 million to build vaccine platform AstriVax will draw on technology developed at the KU Leuven Rega Institute (Belgium) to develop novel vaccines that are easy to produce, have reduced cold chain requirements, and offer broad and long-lasting protection against various pathogens. Closing on…..
Why low DNA methylation at H3K27me3 sites for gene repression In our cells, genes associated with alternative cell fate have to be silenced. DNA methylation and H3K27me3 on the histone are two of the most prevalent chromatin modifications that control the epigenetic gene silencing. These two modifications are mutually exclusive…..