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Date Company Compound Disease Type of agreement Therapeutic area Type of Information
2016-05-04 University of Pennsylvania

R&D

collaboration

R&D agreement
2016-05-04 Audentes Therapeutics (USA - CA) University of Pennsylvania (US - PA) AT342 Crigler-Najjar Syndrome collaboration - research Rare diseases - Genetic diseases - Hepatic diseases - Liver diseases Collaboration agreement
2016-05-03 Orchard Therapeutics (UK) University College London (UK) Great Ormond Street Hospital for Children NHS Foundation Trust (UK) the University of Manchester (UK) the University of California Los Angeles (USA - CA) Boston Children’s Hospital (USA - MA) gene therapies

R&D

Rare diseases - Genetic diseases R&D agreement
2016-05-03 Ionis Pharmaceuticals (USA - CA) Kastle Therapeutics (USA - IL) Kynamro® (mipomersen sodium) homozygous familial hypercholesterolemia (HoFH)

product acquisition

Rare diseases - Genetic diseases - Metabolic diseases Product acquisition
2016-05-03 RXi Pharmaceuticals (USA - MA) Thera Neuropharma (USA - PA) self-delivering RNAi (sd-rxRNA®) compounds targeting superoxide dismutase 1 (SOD1) amyotrophic lateral sclerosis (ALS)

licensing

Neurodegenerative diseases Licensing agreement
2016-05-03 Ipsen (France) Oncodesign (France)

R&D

Cancer - Oncology R&D agreement
2016-05-02 Merck KGaA (Germany) new facility at Martillac (France)

opening of new premises

Technology - Services Opening of new premises
2016-05-02 Bind Therapeutics (USA - MA)

restructuring

Cancer - Oncology Restructuring
2016-04-29 Pfizer (USA - NY) Swedish Orphan Biovitrum (Sobi) (Sweden) ReFacto AF® (EU)/Xytna® (USA) (moroctocog alfa), Kineret® treatment and prophylaxis of bleeding in patients with hemophilia A (congenital factor VIII deficiency), Cryopyrin-Associated Periodic Syndromes (CAPS): neonatal-onset multisystem inflammatory disease (NOMID) Chronic Infantile Neurological, Cutaneous, Articular Syndrome (CINCA) Muckle-Wells Syndrome (MWS) Familial Cold Autoinflammatory Syndrome (FCAS)

manufacturing

production

Hematologic diseases - Genetic diseases - Rare diseases Production agreement
2016-04-29 Ablynx (Belgium) Novartis (Switlzerland)

R&D

Milestone
2016-04-28 Shire (UK - USA)

nomination

Nomination
2016-04-28 Alnylam Therapeutics (USA - MA) RNAi therapeutics

construction of a production plant

Construction of a production plant
2016-04-27 Medday (France)

nomination

Autoimmune diseases - Neurodegenerative diseases - Neurological diseases Nomination
2016-04-26 Ipsen (France) Probi (Sweden) Lactobacillus plantarum 299v (LP299V®) irritable bowel syndrome

licensing

commercialisation

Gastrointestinal diseases - Digestive diseases Licensing agreement
2016-04-26 Abivax (France) PCAS (France) ABX464 HIV infection

production

manufacturing

services contract

Infectious diseases Services contract
2016-04-26 Oxford Biomedica (UK)

nomination

Nomination
2016-04-26 Bionor Pharma (Norway)

resignation

Infectious diseases Resignation
2016-04-26 Galena Biopharma (USA - OR)

nomination

Cancer - Oncology Nomination
2016-04-26 PTC Therapeutics (USA - NJ)

nomination

Rare diseases - Genetic diseases Nomination
2016-04-26 AstraZeneca (UK) Ironwood Pharmaceuticals (USA - MA) lesinurad gout licensing Inflammatory diseases Licensing agreement