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Agreements

Date: 2018-01-22

Type of information: Collaboration agreement

Compound: antibodies using Iontas’ proprietary Mammalian Display Technology

Company: Iontas (UK) Sanofi (France)

Therapeutic area: Technology - Services

Type agreement: collaboration

Action mechanism: monoclonal antibody

Disease:

Details:

  • • On January 22, 2018, Iontas, a leader in the discovery and optimisation of fully human antibodies, announced that it has signed an agreement with Sanofi to discover antibodies using Iontas’ proprietary Mammalian Display Technology.
  • Iontas’ platform allows for the construction of large libraries of monoclonal cell lines each displaying a different IgG-formatted antibody on the cell surface. Novel binders can be isolated from the libraries by using fluorescence-activated cell sorting on the basis of antigen binding. Importantly, the system also has the potential to identify clones with development liabilities, such as self-aggregation, during the initial discovery phase.

Financial terms:

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Is general: Yes