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Date: 2016-01-22

Type of information: Nomination

Compound:

Company: Adaptimmune (UK)

Therapeutic area: Cancer - Oncology - Autoimmune diseases

Type agreement:

nomination

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* On January 22, 2016, Adaptimmune announced that it has augmented its manufacturing leadership to prepare for clinical and commercial scale up with the additions of William Buecheler as Vice President, Manufacturing Operations, and Phil Bassett as Head of Process Development. Mr. Buecheler is responsible for Adaptimmune\'s global manufacturing operations, including contract and in-house manufacturing activities, and is leading the implementation of scale up plans designed to achieve commercial manufacturing capability. Mr. Bassett is responsible for process development activities including leading Adaptimmune’s T-cell and lentivirus process development.
Bill Buecheler brings to Adaptimmune over 25 years of industry experience in manufacturing operations, facility planning and expansion, leadership of FDA pre-approval inspection and document preparation, and manufacturing process improvements. He joins Adaptimmune from Novartis Pharmaceuticals, where he acted as the Director and Process Unit Head, with responsibility for overall manufacturing operations of the Cell and Gene Therapy Process Unit. As a member of the senior leadership team, his responsibilities included manufacturing efforts to support the scale up operations for Novartis’ CTL019 chimeric antigen receptor product for treatment of ALL and CLL patients. Prior to joining Novartis, he worked and consulted for numerous pharmaceutical and biotech companies in areas including facility build out and expansion, change control, process improvement, cycle time reduction and critical path project management. Mr. Buecheler earned his Master of Business Administration degree from Syracuse University.
Phil Bassett brings with him over 15 years of process manufacturing experience in CMO, small biotech and large biopharma environments. Most recently, Mr. Bassett served as Head of Manufacturing Development for the Cell Therapy Catapult, a UK-based Center of Excellence in cell therapy, where he was responsible for technology transfer and providing late stage commercial manufacturing, scale-up and process industrialization expertise. Prior to the Cell Therapy Catapult, he served at UCB Celltech as the Associate Director and Head of Fermentation Process Sciences, managing the upstream development team working on clinical and commercial processes, and leading process development, scale up and technology transfer efforts. He also spent several years in roles of increasing responsibility with Cobra Biomanufacturing plc, a UK-based international contract development and manufacturing organization providing biologics for pre-clinical and clinical supply.

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