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Agreements

Date: 2012-11-01

Type of information: R&D agreement

Compound: macrocycles, against several high-value pharmaceutical targets specified by Boehringer Ingelheim

Company: Ensemble Therapeutics (USA) Boehringer Ingelheim (USA)

Therapeutic area: undisclosed

Type agreement:

R&D

Action mechanism:

Disease: undisclosed

Details:

Ensemble Therapeutics has announced the initiation of a research collaboration with Boehringer Ingelheim to discover drug candidates of a novel class of small molecule drugs, called macrocycles, against several high-value pharmaceutical targets specified by Boehringer Ingelheim. The collaboration will deploy Ensemble’s proprietary drug discovery platforms including its Ensemblin™ collection of about 5 million macrocycles to discover and advance novel drug candidates against Boehringer Ingelheim’s drug targets. Boehringer Ingelheim will have the exclusive right to develop and commercialize substances arising from the collaboration.

Financial terms:

Under the terms of the agreement, Ensemble is eligible to receive payments and may receive up to $186 million in success milestones in case of full commercial success of multiple drug products, including an upfront payment and research funding. In addition, Ensemble is eligible to receive royalties on future sales of products that arise from the collaboration. Further details of the agreement were not disclosed.

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